ASSOCIATION BETWEEN MAJOR DIETARY PATTERN AND METABOLIC UNHEALTHY PHENOTYPE IN OVERWEIGHT/OBESITY IRANIAN WOMEN

Background and Aim: No studies have examined the contribution of major dietary patterns to metabolically unhealthy (MUH) phenotypes in obese and overweight people based on Karelis criteria. This study was conducted to evaluate the association of major dietary patterns with metabolically unhealthy overweight/obesity (MUHOW/O).Methods: This cross-sectional study was conducted on 290 overweight and obese women aged 18–50 (BMI≥25 kg/m2). Anthropometric measurements were assessed in all participants. The metabolic healthy (MH) phenotype was defined according to the Karelis criteria. Major dietary patterns were determined using factor analysis of 21 foods groups using a valid and reliable FFQ containing 147 items. Participants’ body composition was assessed by BIA. Serum HDL, LDL, TG, insulin, and hs-CRP levels were quantified by ELISA.Results: According scree plot, three major dietary patterns were extracted: healthy dietary pattern (HDP), western dietary pattern (WDP) and unhealthy dietary pattern (UNHDP). Binary logistic analysis showed that individuals in the in the upper category of WDP had greater odds of MUH phenotype (OR=2.33, 95%CI=1.11-4.91, P=0.02), after confounder factor control. Participants with high adherence to the UNHDP score had high odds of MUH phenotype (OR=1.75, 95%CI=0.98-3.10, P=0.05), after adjustment for BMI, age, and total EI, compared to those with low adherence. Conclusion: The present evidence indicates various significant associations among western and unhealthy dietary patterns and MUHOW/O phenotypes

کلیدواژه ها:

metabolic healthy ، metabolic unhealthy ، dietary pattern ، Karelis criteria ، obesity and overweight