Biobank, Right Drug, Right dose, Right Time

سال انتشار: 1395
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 424

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شناسه ملی سند علمی:

IPMCMED01_134

تاریخ نمایه سازی: 23 آذر 1397

چکیده مقاله:

Two major formats of biobank; population based and disease oriented biobanks have many subgroups in different categories. The development into personalized medicine is highly depends on the researchable and usable data. Biobanks are the important and necessary tools that be used for available large number of samples with enough information of each person for the aims of personalized medicine. Also biobanks can reinforce personalized medicine by finding and verification of interactions between genetic variability and environmental factors such as life style and phenotype of the persons. For the purpose of establishment human biobank, we collected the blood samples from two formats –population based and people with disease- Iranian ethic groups and people with genetic disease. We completed the questionnaire for demographic and other necessary data. Then certified the cell lines and keeping in nitrogen vapor phase with IBRC code number according to standard protocols. We show considerations in setup a biobank, including compliant and governance, bio-samples, risk factor and related data and informatics. Additionally we carefully designed biobanks for provide critical research and infrastructure support for clinical genetics in the era of personalized medicine.

نویسندگان

Mansoureh Farhangniya

human and animal cell banks, Iranian Biological Resource center (IBRC), ACECR, Tehran. Iran

Parvaneh Farzaneh

human and animal cell banks, Iranian Biological Resource center (IBRC), ACECR, Tehran. Iran

Mehrnaz Izadpanah

human and animal cell banks, Iranian Biological Resource center (IBRC), ACECR, Tehran. Iran

Seyed Abolhassan Shahzadeh Fazeli

human and animal cell banks, Iranian Biological Resource center (IBRC), ACECR, Tehran. Iran