Nutrigenomics and Personalized Nutrition

سال انتشار: 1395
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 351

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شناسه ملی سند علمی:

IPMCMED01_137

تاریخ نمایه سازی: 23 آذر 1397

چکیده مقاله:

Like drugs, Nutrients have the ability to interact and modulate molecular mechanisms underlying an organism’s physiology functions. Awareness of different effects of nutrients according to our genetic construction (Nutrigenetics) and how foods and food constituents (Nutrigenomics) may affect gene expression. It is about how our DNA is transcribed into mRNA and then to proteins and provides a basis for understanding the biological activity of food components. Nutrigenomics is applying the sciences of genomics, transcriptomics, proteomics, and metabolomics to human nutrition in order to understand the relationship between nutrition and health. Part of the approach of nutrigenomics involves finding markers of the early phase of diet related diseases; this is the phase at which intervention with nutrition can return the patient to health. Nutrigenomics has been associated with the idea of personalized nutrition based on genotype. While there is hope that nutrigenomics will ultimately enable such personalized dietary advice. It can also be seen as research to provide people with methods and tools who are looking for disease preventing and health promoting foods that match their lifestyles, cultures and genetics. As nutrigenomics seeks to understand the effect of different genetic predispositions in the development of such diseases, once a marker has been found and measured in an individual, the extent to which they are susceptible to the development of that disease will be quantified and personalized dietary recommendation can be given for that person. The aims of nutrigenomics also includes being able to demonstrate the effect of bioactive food compounds on health and the effect of health foods on health, which should lead to the development of functional foods that will keep people healthy according to their individual needs. This article discusses relationship between nurtigenomics and personalized diet.

نویسندگان

Naheed Aryaeian

Department of Nutrition, School of Public Health, Iran University of Medical Sciences,Tehran, Iran