Condensation reaction between 3-acetylcumarine and arylaldehydes in the presence of L-proline

Coumarins are one of the most important group of natural compounds which contain anti-HIV, anti tomour ,anti hypertension, anti osteoporosis, anti allergic, pain killer and preventive of growth and proliferation of microbes .In this research, it is applied a new method for synthesis of coumarin ingredients by using two steps and aldol reaction, which is contain synthesis 3-acetyle coumarin as a primary substance by using a mixture of ethyl acetoacetate and salicylaldehyde and a few drops of ethyl amin and in next step it is containes reaction of 3-acetyle coumarin and benzenaldehyde derivatives in presence of L-proline as a adaptable catalysis by enviroment in alcohol in reflex condition, in this study will be evaluated.The purpose of this research is representing a adaptable synthesis method with enviroment and also the synthesis of coumarin elements by using of L-proline catalysis.