An Efficient One-Pot Synthesis of Novel Heterocycles with Thiohydantoins and Isocyanides

The reaction of stoichiometric amounts of dialkyl acetylenedicarboxylates with alkyl isocyanides and 5,5-diaryl thiohydantoins in toluene and catalytic amount of p-TSA afforded imidazo[2,1-b][1,3]thiazines in good overall yields

کلیدواژه ها:

Thiohydantoin ، Imidazo[2 ، 1-b][1 ، 3]thiazine ، Isocyanide ، Acetylenedicarboxylate ، Zwitterioni