The critical role of liver in PCOs management

Background: Polycystic ovary syndrome (PCOS) is the most common (5-15%) endocrine disorder with serious complications and almost unclear pathophysiology in women of reproductive age. Due to the high prevalence, uncertainty of the causes, medical, familial and social complications of PCOs, revision of the management with another perspective might be helpful. The aim of this study was to investigate the role of liver in the proper function of ovaries in traditional Iranian medicine and may offer new models in the management of PCOs.Methods: This is a descriptive study done by using Traditional Persian Medicine(TPM) references such as Canon of Medicine.Result: PCOs has been described by Persian philosophers under the headings of amenorrhoea, infertility and uterine disorders. TPM scholars noted combination of signs with oligo-amenorrhoea including hirsutism, obesity, acne and infertility which are suggestive for PCOs. According to TPM view points, liver is one of the main organs that receives all blood coming from stomach and bowel through portal vein, manufactures nutrients, and then distributes them to the rest of the body. So liver failure would lead to dysfunction of other organs such as ovarian diseases.Conclusion: Liver is involved with almost all pathways to growth, nutrient supply, energy provision and reproduction.There is an interconnected between the healthy ovaries and proper function of main organs specially liver. It seems that checking up, protecting and strengthening liver function is a fundamental step to achieving or maintaining reproductive system health and may be helpful in PCOs treatment.

کلیدواژه ها:

liver ، Pcos ، Traditional Persian Medicine