BMI in PCOS patients and its importance in infertility treatment

Background: Polycystic ovary syndrome is one of the most common endocrine disorders which may cause obesity but not universally. Typically, these features are associated with hypersecretion of luteinizing hormone and androgens, but with normal or low serum concentrations of follicle-stimulating hormone. The aim of this study is to consider BMI in PCOS patients and its importance in infertility treatment. Methods: This is a clinical trial study. The statistical population is 120 patients with PCOS in clinical , laboratory and transvaginal ultrasound appearance. Data was analyzed by SPSS 19.Result: From 120 PCOS patients, 28 ones (23.3 %) were single and 92 ones ( 76.7%) married. The age ranged between 17-34 years old (mean 25.17). 12.7 % of the cases had regular menstrual cycle, while 87.3% experienced irregular menstruation. 50% of them had oligomenorrhea, 64% had hirsutism and 50% had LH/FSH> 2. Among married cases, 7.5 % were fertile, 67.5% had primary infertility and 25% secondary infertility. 43% of the cases had BMI> 24.9 (over weight and obese), 57% in BMI 15-20. All patients were PCOS in ultrasound examination.Conclusion: In fact, obesity was known as a prevalent factor in PCOS based on the previous investigations. This study indicates that less than half of the cases were obese. Accordingly, in our region there are another factors affect PCOS such as genetic, nutrition and geographic area. So, using usual infertility treatment should be accompanied by complication like OHSS. Therefore, these patients should be administered cautiously for safety doses and duration of drugs because of the side effects in low BMI patients. More studies is suggested.

کلیدواژه ها:

OHSS ، PCOS ، BMI