Developing a Probe for Detection of Sperm Capacitation

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 486

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شناسه ملی سند علمی:

ISERB04_069

تاریخ نمایه سازی: 16 تیر 1397

چکیده مقاله:

Currently, the diagnosis of male infertility is based on results of semen analysis, which includes the evaluation of sperm motility, morphology, and concentration. While based on the World Health Organization (WHO, 2010) normal sperm have concentration of ≥15 × 106/ml, total motility of ≥40%, and morphology as ≥4% normal forms, the functional tests for detection of normal sperm seem to need development. Among them, detection of sperm capacitation not only is important for determining the percentage of normal spermatozoa during semen analysis, but also it is important for determination of the suitable protocols during assisted reproductive technology (ART). In this study a probe for detection of sperm capacitation were developed using biochemical studies. The results indicated that the probe may provide a new diagnostic tool.

کلیدواژه ها:

Sperm capacitation ، Assisted Reproductive Technology (ART) ، World Health Organization (WHO) ، Semen analysis

نویسندگان

Rahman Emamzadeh

Department of Biology, University of Isfahan, Department of Biology, University of Isfahan

Mahboobeh Nazari

Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran