Molecular examination Superoxidation The sides of the mitochondria membrane in adult spermatozoa In mouse models with standard fertility and idiopathic infertility

The sperm motility is due to the formation of transverse waves along sperm whales, which is affected by a very complex molecular process. Given the exact morphology of the sperm, we know that the motor and the energy source required for the regular movement of the sperm by the flagellum, its neck portion. With a closer look and molecular examination, we can see the origin of these movements that have mitochondria in the neck of the sperm. By providing the necessary energy, mitochondria generate fluid and flaccid movements like in a flugelum and direct sperm to the ovule for fertilization. The aim of this study was to investigate genes and molecular pathways affecting the spermatocyte mitochondria of azoospermic and neuromozospermia mouse. In order to investigate the effect of molecular signaling pathways and genetic factors affectingthe mobility of spermatozoids, we need two groups of mice that have at least one successful fertility and the other have infertility due to sperm motility. To record the data before the study And comparing the results between the two groups of sperm analysis experiments for both groups and using the common molecular methods such as Real Time PCR and RT PCR, we will record the data for the desired results of the study.

کلیدواژه ها:

Superoxidation ، energy of mitochondria ، Sperm flaglom ، Andrology ، Idiopathic infertility