Synthesis of Quinoline-3-carbonitrile Derivatives in the Presence of a Novel and Reusable Nanomagnetic Catalyst

One of the interesting choices for the heterogenization of the homogeneous catalysts is thestabilization of catalytic active structure onto the surface of magnetic nanoparticles such asFe3O4 nano particles. This process is an efficient strategy to overcome difficulties connectedto cumbersome process of isolation and separation of the homogeneous catalytic system [1-2].On the other hands applying one-pot multicomponent reactions strategy for the rapid synthesisof target molecules accompanied with economic and ecological insight in highly valuable[3]. In this investigation we combined excellent merits connected with nano magnetic heterogeneouscatalysts and one-pot multicomponent reactions strategy and present an applicableroute for the synthesis of quinoline-3-carbonitrile derivatives under mild reaction conditions(Figure 1).