Small FITC-labeled chitosan nanoparticles: synthesis and characterization

Application of fluorescent nanoparticles has attracted lots of attention in the field of medical imaging. Recently, polymeric chitosan nanoparticles have been used widely as novel drug delivery systems or in tissue engineering applications due to their high biocompatibility and good adhesive properties. We studied the feasibility of production of small FITC-labeled chitosan nanoparticles without changing the initial structure of polymer. Through this study FITC-labeled chitosan nanoparticles with diameters less than 100nm were produced and the effect of FITC-labeling on the size of chitosan nanoparticles was investigated