Synthesis of Biocompatible PEG hydrogel via Click Chemistry for Control release of 2,4-D Herbicide

Synthesis of PEG based hydrogel from concurrent copper (I)-catalyzed azide- alkyne cycloaddition click chemistry was demonstrated. Firstly, PEG and penaerythritol were functionlized with azide and alkyne groups respectivily. When the solutions of the two derivatives were mixed together, a crosslinking reaction, a type of Huisgens 1,3- dipolar azide- alkyne cycloaddition in the presence of Cu(I) catalyst occurs. The PEG based hydrogel exhibit high swelling ratios and good mechanical properties. 2,4-D was loaded into the hydrogels and release of this herbicide is being investigated

کلیدواژه ها:

Click Chemistry ، Polyethylene glycol ، Hydrogel ، Control Release ، Herbicide