Comparison of Th1/Th2 and Treg/Th17 ratios between wet and dry cupping therapies in Persian medicine

سال انتشار: 1399
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 422

فایل این مقاله در 11 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_AJP-10-1_004

تاریخ نمایه سازی: 24 فروردین 1399

چکیده مقاله:

Objective: In Persian medicine (PM), wet-cupping therapy (WCT) is the most utilized approach. WCT is mostly done between the shoulders, which is referred to as hejamt-e-aam in the Persian language. CD4+T cells also refer to T helper lymphocytes play a critical role in the immune system. Naïve CD4+ T cells differentiate into at least four subsets, T helper 1 (Th1), T helper 2 (Th2), T helper 17 (Th17), and T regulatory (Treg) cells. The master regulator controlling each subset have been defined as follows, Tbet (Th1), Gata3 (Th2), RORγt (Th17), FoxP3 (Treg). The purpose of this study was to compare the effect of WCT and dry-cupping therapy (DCT) on the ratios of Th1/Th2 and Treg /Th17 in healthy individuals. Material and Methods: Participants were divided randomly into two groups of 41 men in the WCT group and 40 men in the DCT group. Blood was taken, before, one and four weeks after the intervention. RNA was extracted from the peripheral blood mononuclear cells and the expression of T-bet, GATA-3, RORγt, and Foxp3 genes were determined by using SYBR green RT-PCR technique. Results: The results showed that WCT increased the expression ofGATA-3, RORγt, and Foxp3 transcription factor genes (p=0.009, p=0.001, and p=0.021, respectively). Although in the WCT group, the ratio of Foxp3/RORγt increased (p=0.048), but the ratio of T-bet/GATA-3 (Th1/Th2) decreased (p=0.971). Conclusion: Our findings indicated that WCT may regulate the T subsets of lymphocyte and reduce inflammation.

کلیدواژه ها:

Wet Cupping Therapy ، Subsets of T lymphocyte ، Persian Medicine

نویسندگان

reza Soleimani

Department of Persian medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Mojgan Mohammadi

Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.|Immunology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Seyed Ahmad Saghebi

Department of Internal Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Ali Taghipour

Department of Epidemiology and Biostatistics, Health School, Mashhad University of Medical Sciences, Mashhad, Iran.

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Abbas AK, Lichtman AH, Pillai S. 2015. Cellular and molecular ...
  • Ahmed SM, Madbouly NH, Maklad SS, Abu-Shady EA. 2005. Immunomodulatory ...
  • Al-Bedah AM, Elsubai IS, Qureshi NA, Aboushanab TS, Elgi, El-Olemy ...
  • AlBedah AM, Khalil A, Elolemy AA, Hussein M, AlQaed A, ...
  • Arslan M, Yeşilçam N, Aydin D, Yüksel R, Dane S. ...
  • Askari VR, Alavinezhad A, Boskabady MH. 2016. The impact of ...
  • Askari VR, BaradaranRahimi V, Rezaee SA, Boskabady MH. 2018. Auraptene ...
  • Askari VR, Fereydouni N, BaradaranRahimi V, Askari N, Sahebkar AH, ...
  • Askari VR, Fereydouni N, Rahimi VB, N. Askari A H, ...
  • Askari VR, Rezaee SA, Abnous K, Iranshahi M, Boskabady MH. ...
  • Askari VR, Shafiee-Nick R. 2019. Promising neuroprotective effects of β-caryophyllene ...
  • Askari VR, Shafiee-Nick R. 2019. The protective effects of β-caryophyllene ...
  • Bacchetta R, Barzaghi F, Roncarolo MG. 2018. From IPEX syndrome ...
  • Boskabadi J, Askari VR, Hosseini M, Boskabady MH. 2018. Immunomodulatory ...
  • Boskabady MH, Hashemzehi M, Khazdair MR, Askari VR. 2016. Hydro-ethanolic ...
  • Cao H, Han M, Zhu X, Liu J. 2015. An ...
  • Cao H, Zhu C, Liu J. 2010. Wet cupping therapy ...
  • Dons koi BV, Chernyshov VP, Osypchuk DV, Baksheev SM. 2016. ...
  • Ebrahimi AE, H. Moulavi SG, Mousavi, BornaManesh A, Yaghoubi M. ...
  • El Sayed SM, Al-quliti AS. Hijamah: in light of modern ...
  • El Sayed SM, Baghdadi H, Abou-Taleb A, H. S. Mahmoud ...
  • Fasching P, Stradner M, Graninger W, Dejaco C, Fessler J. ...
  • Goldberg DP, Hillier VF. 1979. A scaled version of the ...
  • Goodwin J, McIvor RA. 2011. Alternative therapy: cupping for asthma. ...
  • Grant CR, Liberal R, Mieli-Vergani G, Vergani D, and Longhi ...
  • Hashemzehi M, Khazdair M, Kiyanmehr M, Askari V, Boskabady MH. ...
  • Kianmehr M, Rezaei A, Hosseini M, Khazdair MR, Rezaee R, ...
  • Kidd P. 2003. Th1/Th2 balance: the hypothesis, its limitations, and ...
  • Kim JI, Lee MS, Lee DH, Boddy K, Ernst E. ...
  • Kordafshari G, Ardakani MRS, Keshavarz M, Esfahani I, Nazem M, ...
  • Kordafshari G, Kenari HM, Esfahani MM, Ardakani MRS, Keshavarz M, ...
  • Lee GR. 2018. The Balance of Th17 versus Treg Cells ...
  • Lubberts E. 2010. Th17 cytokines and arthritis. Semin Immunopathol, 32:43–53. ...
  • Mahdavi MRV, Ghazanfari T, Aghajani M, Danyali F, Naseri M. ...
  • Mahmoud HS, Abou-El-Naga M, Omar NAA, El-Ghazzawy HA, Fathy YM, ...
  • Maruyama T, Kono K, Mizukami Y, Kawaguchi Y, Mimura K, ...
  • Montazer R, Namavary D. 2016. Comparison biochemistries of obtained blood ...
  • Rahimi VB, Askari VR, Shirazinia R, Soheili-Far S, Askari N, ...
  • Rahimi VB, Shirazinia R, Fereydouni N, Zamani P, Darroudi S, ...
  • Refaat B, El-Shemi AG, Ebid AA, Ashshi A, andBaSalamah MA. ...
  • Tabatabaee A, Zarei M, Javadi SA, Mohammadpour A, Bidaki AA. ...
  • Wang Qf, Wang GY. 2008. Therapeutic effect observation on treatment ...
  • Yao J, Li N. 2007. Clinical observation on pricking and ...
  • Yao X, Shan S, Zhang Y, Ying H. 2011. Recent ...
  • Zarei M, Hejazi S, Javadi SA, Farahani H. 2012. The ...
  • نمایش کامل مراجع