Evaluation of the anti–depressant activity of Myristica fragrans (Nutmeg) in male rats
محل انتشار: مجله گیاهان دارویی ابن سینا، دوره: 2، شماره: 2
سال انتشار: 1391
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 251
فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_AJP-2-2_003
تاریخ نمایه سازی: 1 مهر 1398
چکیده مقاله:
Objective: The present study was undertaken to evaluate anti-depressant activity of Myristica fragrans(MS).
Materials and Methods: Male Wistar rats were subjected to imipramine and herbal extract ofMS for their antidepressant activity using Forced Swimming Test (FST), Reserpine Reversal Test (RRT), Haloperidol-Induced Catalepsy (HIC), and Pentobarbitone Sleeping Time (PST).
Results: Administration of MS and imipramine revealed a statistically significant reduction in immobility time in FST, RRT, and protection against HIC, compared to the control group. However, there was no significant potentiation of PST.
Conclusion: Our study demonstrated the potential antidepressant activity of MS.
کلیدواژه ها:
نویسندگان
Ghulam Moinuddin
Department of Pharmacology, Al-Ameen College of Pharmacy, Near Lalbagh Main Gate, Bangalore-۵۶۰۰۲۷. India
Kshama Devi
Department of Pharmacology, Al-Ameen College of Pharmacy, Near Lalbagh Main Gate, Bangalore-۵۶۰۰۲۷. India
Deepak Kumar Khajuria
Department of Pharmacology, Al-Ameen College of Pharmacy, Near Lalbagh Main Gate, Bangalore-۵۶۰۰۲۷. India