A quick overview on some aspects of endocrinological and therapeutic effects of Berberis vulgaris L.
محل انتشار: مجله گیاهان دارویی ابن سینا، دوره: 5، شماره: 6
سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 608
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شناسه ملی سند علمی:
JR_AJP-5-6_002
تاریخ نمایه سازی: 1 مهر 1398
چکیده مقاله:
Many herbaceous plants contain compounds that have biological effects in addition to their medicinal properties. They have compounds with numerous properties, including hypo lipidemic, hypoglycemic, antioxidant, and hepato protective ones, which have been analyzed at different levels. One of these plants, with the scientific name of Berberis vulgaris, is barberry. The most important compounds identified in this plant are berberine, oxycontin, palmatine, bervulcine, berbamine, columbamine, jatrorrhizine, coptisine, and berbamine. In addition to alkaloids, organic acids such as chelidonic acid, citric acid, malic acid, resin, tannin, pectinic, and mucilagic substances are among the ingredients of barberry. In this paper, it was attempted to determine the role and effect of the extract of barberry on various body organs. The results showed that berberine actually increases insulin sensitivity and is capable of inhibiting alpha glucosidase, adipogenesis, and thus acts as an anti-obesity and hypoglycemic agent. Berberine reduces the density of serum cholesterol and triglycerides and can improve the function of liver enzymes, therefore, it can be suggested as a hypo lipidemic and hepato protective plant extract. The hepato protective effects of this extract are probably due to its antioxidant properties. Studies showed that barberry have numerous health benefits, including anti-inflammatory ones. Moreover, it can be used as a medicinal herb to treat a variety of disorders, such as diabetes, liver disease, gallbladder pain, digestive, urinary tract diseases, and gallstones. However, more studies on this issue and doing more focused and intensive researches in this field are recommended.
کلیدواژه ها:
نویسندگان
Ali Zarei
Young Researchers and Elite Club, Abadeh Branch, Islamic Azad University, Abadeh, Iran
Saeed Changizi Ashtiyani
Department of Physiology, Arak University of Medical Sciences, Arak, Iran
Soheila Taheri
Education Development Center, Arak University of Medical Sciences, Arak, Iran
Majid Ramezani
Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
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