In vitro and in vivo evaluations of Pelargonium roseum essential oil activity against Trichomonas gallinae

سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 387

فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_AJP-8-2_004

تاریخ نمایه سازی: 18 تیر 1398

چکیده مقاله:

Objective: Pelargonium roseum Willd.(Geraniaceae) is widely grown as an ornamental plant due to its strong pleasant rose-like odor. The present study evaluates the antitrichomonal effect of P. roseum essential oil (EO) against Trichomonas gallinae both in vitro and in vivo and compares it to that of metronidazole (MTZ) as a standard antitrichomonal drug. Materials and Methods: In vitro assays were accomplished in multi-well plates containing MTZ and EO at final concentrations of 2.5, 5, 10, 20, 50, and 100 μg/mL. In vivo assay was carried out on 40 experimentally infected pigeons receiving MTZ and EO at doses of 25 and 50 mg/kg. Results: The 24-hr MIC of MTZ was 10 µg/mL, while for EO it was 20 µg/mL. Treatment with MTZ 50 mg/kg after 4 days led to full recovery of infected pigeons however EO 50 mg/kg resulted in the same outcome after 5 days. No mortality or clinical side effects were seen in treated birds. Conclusion: The present study introduced P. roseum EO as a potent natural antitrichomonal agent effective against T. gallinae. Bioactive components of P. roseum can be used as potential therapeutic compounds in development of novel antitrichomonal drugs.

نویسندگان

Mohaddeseh Abouhosseini Tabari

Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran

Mohammad reza Youssefi

Department of Veterinary Parasitology, Babol Branch, Islamic Azad University, Babol, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Boal CW, Mannan RW, Hudelson KS. 1998. Trichomoniasis in Cooper ...
  • Carmen G, Hancu G.2014. Antimicrobial and antifungal activity of Pelargonium ...
  • Fakhrie-Kashan Z, Arbabi M, Delavari M, Taghi-Zadeh M, Hooshyar H, ...
  • George D, Biron J, Jolly G Duvallet G, Sparagano O. ...
  • Gerhold RW, Yabsley MJ, Smith AJ, Ostergaard E, Mannan W, ...
  • Khallaayoune K, Biron J, Chaoui A, Duvallet G. 2009.  Efficacy ...
  • Lis-Balchin M, Hart S, Deans S, Eaglesham E. 1996. Potential ...
  • Lumeij JT, Zwijnenberg RJ. 1990. Failure of nitro-imidazole drugs to ...
  • Munoz E, Castella J, Gutierrez JF. 1998. In vivo and ...
  • Rezai A, Mohajeri D, Pashazadeh M. 2008. Study of histometric ...
  • Rouffaer LO, Adriaensen C, De Boeck C, Claerebout E, Martel ...
  • Sansano-Maestre J, Garijo-Toledo MM, Gómez-Muñoz MT. 2009. Prevalence and genotyping ...
  • Seddiek A, El-Shorbagy MM, Khater HF, Ali AM. 2014. The ...
  • Stockdale JE, Dunn JC, Goodman SJ, Morris AJ, Sheehan DK, ...
  • Tabari MA, Youssefi MR, Esfandiari A, Benelli G. 2017a. Toxicity ...
  • Tabari MA, Youssefi MR, Moghadamnia AA. 2017b. Antitrichomonal activity of ...
  • Youssefi MR, Tabari MA, Moghadamnia AA. 2017. In vitro and ...
  • نمایش کامل مراجع