Health Technology Assessment of Homeopathy in Treatment of Knee Osteoarthritis: Comparison with Non-Steroidal Anti-Inflammatory Drugs

سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 378

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شناسه ملی سند علمی:

JR_EBHPME-1-2_003

تاریخ نمایه سازی: 27 مرداد 1397

چکیده مقاله:

Background: Osteoarthritis is the most common joint disease in humans, whichis the greatest cause of physical disability among the elderly in developedcountries. Homeopathy is a specific therapy that treats patients based on precisestimulation of the immune and vital systems by certain homeopathy medications.Given the widespread use of this technology, in this article, we comparedhomeopathy Health Technology with non-steroidal anti-inflammatory drugs inthe treatment of osteoarthritis.Methods: In this study, Health Technology Assessment (HTA) was employed tocompare homeopathy treatment with non-steroidal anti-inflammatory drugs(NSAIDs), by reviewing clinical trials. The study population included patients withknee osteoarthritis; the intervention group included homeopathy, and the controlgroup comprised routine medical treatment (NSAID) and outcomes measuredincluded efficacy, safety, and cost effectiveness. The most important electronicmedical databases were searched for relevant articles published from 2000 to 2016,including The Cochrane Library, Cochrane Central Register of Controlled Trials(CENTRAL); Center for Reviews and Dissemination, University of York (CRD;NHS EED), Trip; PubMed; EMBASE and Google Scholar.Results: Effectiveness was measured by indicators of pain and motor function.Total changes in VAS index revealed about 34 units decrease in the interventiongroup, while there was 12 units reduction in the control group. Reducing theconsequences of pain and knee function problems were 10 points more in theintervention group in comparison to the control group. Safety outcomes weremeasured via skin reactions (and sensitivity) which were lower in the interventiongroup. In terms of cost-effectiveness, the results revealed that for each unit ofpain relief, more cost was spent in homeopathy method.Conclusion: Given that the overall costs of both treatments were low, even withthe higher effectiveness and safety of homeopathy treatment, compared withNSAIDs, homeopathy is preferable.

نویسندگان

Hedayat Salari

Department of Health Policy, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran

Mohammad Reza Ravanbod

Department of Internal Medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran

Ali Akbari Sari

Department of Health Economics and Management, School of Public Health, Tehran University of Medical Sciences,Tehran, Iran

Atefeh Esfandiari

Department of Health Policy, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran