Functional assessment of CODM gene in different cultivar of Papaveraceous species via in silico analysis

سال انتشار: 1393
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 579

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شناسه ملی سند علمی:

JR_IJABBR-2-5_030

تاریخ نمایه سازی: 26 اسفند 1394

چکیده مقاله:

Medicinal use of the opium poppy (Papaver somniferum L) has ancient history, but the isolation of morphine was not described until the early nineteenth century. Morphine is the most important alkaloid of opium poppy in the last 50 years. In the morphine pathway has been reported togenerate morphine in this species, CODM has a crucial role as the gene coding the enzymeresponsible for demethylation of codeine to morphine. In this study we extract of CODM genesequence from Papaver fogax and Papaver oriental. The sequence of this gene via in silico technique converted to the protein sequence. After this step we use the bioinformatics tools for analysis of these sequences.

نویسندگان

Seyedeh Habibeh Hosseini

Department of Reclamation of Arid and Mountainous Region, Natural Resources Factually,the University of Tehran, Karaj, Iran

Hossein Azarnivand

Department of Reclamation of Arid and Mountainous Region, Natural Resources Factually,the University of Tehran, Karaj, Iran

Mohammad Reza Naghavi

Agronomy and Plant Breeding Department (APBD), College of Agriculture and Natural Resources, the University of Tehran, Karaj, Iran