Coexisting Pituitary Adenoma and Superasellar Meningioma: A Coincidence or Causation Effect? Report of Two Cases and Review of Literature

Background and Importance:The coexistence of pituitary adenoma and another type of brain tumor is a very rare clinicalscenario. Even though such a presentation can be an incidental event but the possible pathogenesis of coexistence ofdifferent lesions in the sella and suprasellar region has not yet been elucidated.Case Presentation: Two cases of concomitant sellar and suprasellar region tumors are reported. A 37-year-old lady withProlactinoma and a suprasellar meningioma and a 42-year-old Acromegalic man with suprasellar meningioma and apituitary adenoma (PA).Conclusion Both meningiomas were removed transcranially while the Prolactinoma could be managed medically and thegrowth hormone (GH) secreting adenoma was removed trans-sphenoidally. The visual problems and hormonal imbalancesof both patients improved postoperatively and there has been no sign of recurrence of the lesions after a mean of fiveyears follow up. The literature is reviewed on this topic and the possible pathogenesis and management protocol of similarlesions are discussed.

کلیدواژه ها:

Acromegaly ، Multiple primary brain tumor ، Prolactinoma ، Suprasellar meningioma ، Pituitary adenoma