Expression of Human Kallikreins 4, 8, 10, 11 and 13 in Pleomorphic Adenomas and Mucoepidermoid Carcinomas

سال انتشار: 1395
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 282

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شناسه ملی سند علمی:

JR_IJP-11-4_004

تاریخ نمایه سازی: 1 مهر 1398

چکیده مقاله:

Background: In cancers of prostate, breast, oropharynx, lung, hypopharynx and skin, human tissue kallikreins has been demonstrated as a main role in these problems. There are many research works in which some human tissue kallikreins are expressed in salivary glands. In the present study, the main goal was to determine expression of human tissue kallikreins 4, 8, 10, 11 and 13 in pleomorphic adenomas and mucoepidermoid carcinomas. Methods: Sixty-six specimens (45 cases of pleomorphic adenomas and 21 cases mucoepidermoid carcinomas) were selected for final analysis by immunohistochemistry. For doing association test, clinical parameters obtained from the patients’ medical charts, which included age, gender were used and the nonparametric tests employed for statistical analyses. Results: The expression of human kallikreins 4, 8, 11 and 13 was more prominent in benign and malignant tumors compared to that in normal tissues and the difference was significant. In addition, the expression of human kallikreins 4, 8, 10 and 11 in malignant tumors was more than that in benign tumors, with statistically significant differences. Conclusion: The differences in the levels of human kallikreins 4, 8, 11 and 13 suggest that kallikreins may benefit in determining tumor behavior of salivary gland tumors. 

نویسندگان

Maryam Alsadat Hashemipour

Kerman Dental and Oral Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran | Kerman Social Determinants on Oral Health Research Center, Kerman University of Medical Sciences, Kerman, Iran

Fatemeh Sadat Fatah

Dept. of Oral Medicine, School of Dentistry, Shiraz University International Division, Shiraz, Iran

Mohammad Javad Ashraf

Dept of Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran

Mehrnaz Tahmasebi

Kerman Social Determinants on Oral Health Research Center, Kerman University of Medical Sciences, Kerman, Iran | Kerman Dental and Oral Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran

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  • Hashemipour MS, Zarei MR, Chamani G, Rad M. Malignant salivary ...
  • Koivunen P, Suutala L, Schorsch I, Jokinen K, Alho OP. ...
  • Seifert G, Sobin LH. Histological typing of salivary gland tumors. ...
  • Akrish S, Peled M, Ben-Izhak O, Nagler RM. Malignant salivary ...
  • Kiyoshima T, Shima K, Kobayashi I, Matsuo K, Okamura K, ...
  • Darling MR1, Jackson-Boeters L, Daley TD, Diamandis EP. Human kallikrein ...
  • Darling MR, Tsai S, Jackson-Boeters L, Daley TD, Diamandis EP. ...
  • Magklara A, Scorilas A, Katsaros D, Massobrio M, Yousef GM, ...
  • Kishi T, Grass L, Soosaipillai A, Scorilas A, Harbeck N, ...
  • Yousef GM, Polymeris ME, Yacoub GM, Scorilas A, Soosaipillai A, ...
  • Yousef GM, Yacoub GM, Polymeris ME, Popalis C, Soosaipillai A, ...
  • Darling MR, Tsai S, Jackson-Boeters L, Daley TD, Diamandis EP. ...
  • Diamandis EP, Yousef GM. Human tissue kallikreins: a family of ...
  • Hashem NN, Mara TW, Mohamed M, Zhang I, Fung K, ...
  • E. Immunoperoxidase technique in histopathology: applications, methods, and controls. J ...
  • Eveson JW, Auclair P, Gnepp DR. Salivary gland tumours. In: ...
  • Ellis GL, Auclair PL. Atlas of tumor pathology. Tumors of ...
  • Anisowicz A, Sotiropoulou G, Stenman G, Mok SC, Sager R. ...
  • Petraki CD, Gregorakis AK, Papanastasiou PA, Karavana VN, Luo LY, ...
  • Petraki CD, Karavana VN, Skoufogiannis PT, Little SP, Howarth DJ, ...
  • Allred DC, Clark GM, Elledge R, Fuqua SA, Brown RW, ...
  • Tuck AB, O Malley FP, Singhal H, Harris JF, Tonkin ...
  • Borgono CA, Diamandis EP. The emerging roles of human tissue ...
  • Stamey TA, Yang N, Hay AR, McNeal JE, Freiha FS, ...
  • Diamandis EP, Yousef GM, Luo LY, Magklara A, Obiezu CV.. ...
  • Borgono CA, Michael IP, Diamandis EP. Human tissue kallikreins: physiologic ...
  • Obiezu CV, Diamandis EP. Human tissue kallikrein family: applications in ...
  • Kapadia C1, Chang A, Sotiropoulou G, Yousef GM, Grass L, ...
  • Scorilas A, Borgoño CA, Harbeck N, Dorn J, Schmalfeldt B, ...
  • Adib TR, Henderson S, Perrett C, Hewitt D, Bourmpoulia D, ...
  • Petraki CD, Karavana VN, Diamandis EP. Human kallikrein 13 expression ...
  • Darling MR, Jackson-Boeters L, Daley TD, Diamandis EP. Human kallikrein ...
  • Cané S, Bignotti E, Bellone S, Palmieri M, De las ...
  • Zhang Y, Bhat I, Zeng M, Jayal G, Wazer DE, ...
  • Darling MR, Hashem NN, Zhang I, Mohamed AB, Fung K, ...
  • Obiezu CV, Michael IP, Levesque MA, Diamandis EP. Human kallikrein ...
  • Yousef GM, Chang A, Scorilas A ,Diamandis EP: Genomic organization ...
  • Komatsu N, Saijoh K, Toyama T, et al: Multiple tissue ...
  • Nakamura T, Mitsui S, Okui A, et al: Alternative splicingisoforms ...
  • Shigemasa K, Gu L, Tanimoto H, O Brien TJ, Ohama ...
  • Bhattacharjee A, Richards WG, Staunton J. Classification of human lung ...
  • Veveris-Lowe TL, Lawrence MG, Collard RL, Bui L, Herington AC, ...
  • Regezi JA, Zarbo RJ, Batsakis JG. Immunoprofile of mucoepidermoid carcinomas ...
  • Ole-MoiYoi OK, Pinkus GS, Spragg J, Austen KF. Identification of ...
  • Luo LY, Katsaros D, Scorilas A, Fracchioli S, Piccinno R, ...
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