Effects of Fumaria parviflora leaves extract on reproductive parameters in adult male rats
محل انتشار: مجله طب تولید مثل ایران، دوره: 11، شماره: 11
سال انتشار: 1392
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 439
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شناسه ملی سند علمی:
JR_IJRM-11-11_005
تاریخ نمایه سازی: 16 شهریور 1395
چکیده مقاله:
Background: There is growing concern that occupational, environmental and lifestyle factors adversely affect male reproductive health. Fumaria parviflora Lam. is being used traditionally in Persian folk medicine to cure various ailments and has been supposed to have fertility-enhancing properties.Objective: A dose-response study was designed to assess effects of F. parviflora ethanolic leaves extract on reproductive parameters in adult male Wistar rats.Materials and Methods: In this experimental study, healthy adult male rats were treated with 100, 200 and 400 mg/kg/day of F. parviflora leaves extract via gavage for 70 days. Blood samples were collected for determination of testosterone, LH and FSH serum levels. Reproductive organs weight, motility, morphology and density of epididymal sperm, seminiferous tubules diameter and germinal epithelium height were evaluated in each experimental group.Results: The body weight was not affected, while the weights of testis and epididymis were significantly enhanced in rats treated with 200 and 400 mg/kg/day F. parviflora extract. No significant changes were observed in seminal vesicle and ventral prostate weight between experiment groups. Significant increase was found in epididymal sperm density and percent of morphologically normal sperm in extract-treated rats. Serum testosterone levels were significantly higher in rats received 200 and 400 mg/kg/day.Conclusion: The results indicated that ethanolic extract of F. parviflora leaves have a potential to improve reproductive parameters and enhance male fertility
کلیدواژه ها:
نویسندگان
Mehran Dorostghoal
Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Seyyed Mansoor Seyyednejad
Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Lotfollah Khajehpour
Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Ayoob Jabari
Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran.