Prevalence of group B streptococcuscolonization in Iranian pregnant women:A systematic review and meta-analysis

Background: Group B Streptococcus (GBS) is an important pathogen in newborns andpregnant women.Objective: The present study was carried out to estimate the prevalence of GBScolonization in pregnant women in Iran.Materials and Methods: This systematic review and meta-analysis was based onPreferred Reporting Items for Systematic Reviews and Meta-Analysis guideline usingthe national databases including Society for Information Display, Magiran, Irandoc,Iran Medex, and international databases including MEDLINE, Web of Science, Scopus,PubMed, Science-Direct, Cochrane, Embase, Elton Bryson Stephens Company, Centrefor Evidence-Based Medicine, Cumulative Index to Nursing and Allied Health Literature,and Google Scholar, published by 01/30/2017. The I2 index was used to measureheterogeneity between the studies.Results: In a total of 667 documents, 30 (4.49%) were selected. In this study, theprevalence of GBS colonization in 10090 Iranian pregnant women was calculatedas 13.65% [confidence interval (CI): 95%: 10.56–17.45]. Based on geographic region,24.63% [CI: 95%: 11.52–45.06] in the West and 8.75% [CI: 95%: 6.43–11.8] in the Eastwere the highest and lowest areas in Iran, respectively, and were statistically significant(p = 0.001). Also, with regards to swapping sampling area, Vaginal with 11.96%, Vaginaland Rectal with 13.62%, and Anal and Vaginal with 25.63% were the least to thegreatest, respectively, and were statistically significant (p = 0.001).Conclusion: Therefore, based on the recommendation of centers for disease control andPrevention as reported by the Ministry of Health and Medical education, early diagnosis,and screening of high-risk women should be done at 35–37 weeks of pregnancy.

کلیدواژه ها:

Streptococcus agalactiae ، Iran ، Pregnancy ، Prevalence ، Female