Hypertensive disorders of in-vitro fertilization pregnancies: A study from Kosovo
محل انتشار: مجله طب تولید مثل ایران، دوره: 16، شماره: 2
سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 305
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شناسه ملی سند علمی:
JR_IJRM-16-2_002
تاریخ نمایه سازی: 27 مرداد 1397
چکیده مقاله:
Background: Relationships between in-vitro fertilization (IVF), gestational hypertension, and pregnancy outcomes are demonstrated in a number of studies. However, it is still debated if IVF treatment or specific characteristics of infertile patients are responsible for worse obstetrical and neonatal outcomes. Objective: The aim of this study was to investigate maternal characteristics associated with hypertensive disorders (HD) in IVF conceived pregnancies and to assess the obstetrical and neonatal outcomes. Materials and Methods: In this observational, cross-sectional study, 207 pregnant women who underwent IVF treatment were consecutively divided into two groups: a group that had no HD during pregnancy (IVF group) and a group that had HD during pregnancy (IVF+HD group). Maternal, obstetrical and neonatal data of the two groups were compared. Results: Some maternal characteristics were significantly higher in IVF+HD compared to IVF group such as: older age (p=0.0001), primiparity (p=0.038), obesity (p=0.0001), and cigarette smoking (p=0.0001). There were no significant differences between the groups in regard to obstetrical outcomes besides premature rupture of membranes time that was significantly higher in IVF+HD group compared to IVF group (p=0.036). In regard to neonatal outcomes, the only statistically significant difference was in the 5th min Apgar score, which was higher in IVF+HD group compared to IVF group without HD (p=0.002). Conclusion: With regard to significantly higher differences in maternal characteristics of IVF conceived pregnancies complicated with HD, compared to uncomplicated ones, development of a specific national prevention measure for HD of IVF conceived pregnancies in Kosovo is strongly suggested. In addition, setting up of a national registry is recommended in order to evaluate the outcomes of IVF treatments properly.
کلیدواژه ها:
نویسندگان
Merita Vuniqi-krasniqi
M.D, Department of Gynecology, University Clinical Center of Kosova, Medical Faculty, University of Pristine, Prishtine, Kosovo
Myrvete Pacarada
M.D, Ph.D, Department of Gynecology, University Clinical Center of Kosova, Medical Faculty, University of Pristine, Prishtine, Kosovo.
Qëndresë Daka
M.D, Ph.D, Department of Pathophysiology, University Clinical Center of Kosova, Medical Faculty, University of Pristine, Pristine, Kosovo
Zeqir Dervishi
M.D, Ph.D, Department of Gynecology, University Clinical Center of Kosova, Medical Faculty, University of Pristine, Prishtine, Kosovo