Hospital-Acquired Infections, Bacterial Causative Agents And Antibiotic Resistance Pattern In Intensive Care Units At Teaching Hospitals In North Of Iran

aim: HAIs (Hospital-Acquired Infections) remain a major problem in ICUs. The purpose of this study is survey ofHAIs and antibiotic susceptibility patterns of causative agent among patients admitted in ICUs.Methods: A retrospective study was conducted in three teaching hospitals related to Mazandaran University ofMedical Sciences in 2012-2014. The incidence, clinical presentation, risk factors, causative agents and antibioticresistance pattern of bacteria analyzed by SPSS (ver. 16) and Descriptive statistics were used.Results: The incidences of HAIs were 4.13%. The most common HAIs were respiratory infection 49.1%, woundinfection 26.3%, UTI 16.7%, and blood Infection 7.9%. P. aeruginosa 42.1%, Acinetobacter spp. 21.05%,Enterobacteriaceae 19.29% and S. aureus 12.28% were the most bacteria isolated. We found that 35% ESBL and14.58% carbapenemase-producer Pseudomonas spp. Also 60% of Acinetobacter spp were MDR and 14.28% ofS.aureus was resistant to niVnmocnaV.Conclusion: This article suggests that the prevalence of HAIs in ICUs of teaching hospitals in northern Iran is falselow. Diagnosing of NI in our area focused on physician diagnosis and clinical criteria for reporting HAIs, The rateof inappropriate administration of antibiotics is very high in our region also significant resistance in organismssuch as Acinetobacter spp, P. aeruginosa, Enterobacteriaceae, S. aureus to the most commonly used antibiotics hasbeen increasing. Infection control procedures must be implemented carefully and Antibiotic resistance patterns oforganisms causing HAIs should be checked periodically to guide empirical antibiotic therapy.

کلیدواژه ها:

Hospital-Acquired Infection ، ICUs ، Antibiotic resistance