Prevalence of Bilirubin Encephalopathy in Calabar, South-South Nigeria: A Five-year Review Study
محل انتشار: مجله علمی ناباروری ایران، دوره: 7، شماره: 1
سال انتشار: 1395
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 259
متن کامل این مقاله منتشر نشده است و فقط به صورت چکیده یا چکیده مبسوط در پایگاه موجود می باشد.
توضیح: معمولا کلیه مقالاتی که کمتر از ۵ صفحه باشند در پایگاه سیویلیکا اصل مقاله (فول تکست) محسوب نمی شوند و فقط کاربران عضو بدون کسر اعتبار می توانند فایل آنها را دریافت نمایند.
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_IRJN-7-1_002
تاریخ نمایه سازی: 9 مهر 1398
چکیده مقاله:
Background: Bilirubin encephalopathy is a clinical syndrome, associated with bilirubin toxicity in the central nervous system, resulting in chronic and permanent sequelae. It has been estimated that approximately 60% and 80% of term and preterm newborns develop jaundice in the first week of life, respectively. In the present study, we aimed to determine the prevalence, morbidity, and mortality of bilirubin encephalopathy in the neonatal unit of the University of Calabar Teaching Hospital, Calabar, Nigeria. Methods: In this retrospective, descriptive review, medical records of all newborns, diagnosed with bilirubin encephalopathy over the past five years (from January 2010 to December 2014), were studied. Information retrieved from the medical records included age, sex, presence of fever, duration of disease, place of delivery, causes of the disease, and selected treatments. Variables such as hospital discharge, discharge against medical advice, and mortality were also evaluated. Results: Out of 2,820 newborns, 21 (0.74%) cases were admitted on account of bilirubin encephalopathy. Among these affected cases, 17 (81%) were male and 4 (19%) were female (male-to-female ratio of 5:1). Based on the findings, 18 newborns (85.7%) had pyrexia, while 8 (38.1%) and 6 (28.6%) cases were hypertonic and hypotonic, respectively upon admission. Only 33.3% of deliveries took place in healthcare facilities. The established factors responsible for jaundice included infection, i.e., septicemia (n=15, 71.4%), ABO incompatibility (n=4, 19.1%), and glucose-6-phosphate-dehydrogenase (G6PD) deficiency (n=2, 9.5%). The mean maximum total bilirubin level in subjects was 321.3 μmol/L (range: 242.5–440.3 μmol/L). Also, mortality was reported in 4 (19%) out of 21 cases. Conclusion: Based on the findings, neonatal septicemia is associated with bilirubin encephalopathy. Therefore, identification and prompt treatment are of utmost importance in preventing the associated morbidity and mortality.
کلیدواژه ها:
نویسندگان
Sunny Oteikwu Ochigbo
Department of Pediatrics, University of Calabar, Calabar, Nigeria
Ifeoma Venn
Department of Pediatrics, University of Calabar Teaching Hospital, Calabar, Nigeria
Kingsley Anachuna
Department of Pediatrics, University of Calabar Teaching Hospital, Calabar, Nigeria
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :