An alternative mathematical modeling of the scintillation camera and framework for performance analysis of gamma-ray positioning algorithms
محل انتشار: مجله پزشکی هسته ای ایران، دوره: 26، شماره: 2
سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 301
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شناسه ملی سند علمی:
JR_IRJNM-26-2_007
تاریخ نمایه سازی: 19 بهمن 1398
چکیده مقاله:
Introduction: Substantive amount of work has been done in modeling and analyzing the scintillation camera system processes including positioning and image formation. The goal of this work is to develop a framework for analyzing performance of nonlinear positioning methods upon construction of a mathematical model of the system. In this study, the photodetector array counts are assumed to follow a multinomial distribution. Methods: We studied effects of several parameters on system performance, including photomultiplier tube (PMT) non-uniform response, gains, shape, size and positioning methods. This was done by constructing linearity and resolution maps, feeding the system a uniform grid of point sources showing the distorted output along with associated blurring intensity. The spatial resolution and linearity parameters are used to evaluate the performance of simulated scintillation camera. Results:The study findings revealed that the square PMT is the best option due to better fitting and quality especially near the edge of the detector and also ability to cover the rectangular crystal area with minimum numbers of PMTs. Also, the resolution resulted from CSE is 5% and 20% better than center of mass and modified center of mass respectively. Conclusion: We showed that the rectangular gamma camera accompanied by an array of square PMTs can introduce the optimum performance regarding linearity and resolution if the nonlinear method, called CSE, is used as positioning method. Further evaluation is needed to evaluate the performance of the proposed gamma camera in practice.
کلیدواژه ها:
نویسندگان
Behnoosh Teimourian Fard
Department of Energy Engineering and Physics, Amirkabir University of Technology, Tehran, Iran|Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran
Mojtaba Shamsaei Zafarghandi
Department of Energy Engineering and Physics, Amirkabir University of Technology, Tehran, Iran
Soheil Hosseini
Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran
Hamid Sabet
Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
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