Vitamin D: Is There a New Era

Background: In recent decades, much interest has been focused oninvestigating new roles of vitamin D in human body beyond the mineral-ionhomeostasis. Methods: By searching medical databases such as PubMed, over16000 articles were found which have been published since 2000 on novelaspects of vitamin D in health and diseases. Results: Of great interest was theeffects of vitamin D on decreasing the risk of several chronic illnesses,including common cancers, autoimmune, infectious, and cardiovasculardiseases. In this review, the new roles of vitamin D that have recently beeninvestigated were addressed. Conclusions: Due to the vast prevalence ofvitamin D deficiency worldwide, it seems that time has come to conduct welldesignedclinical trials and meta-analysis to explore the effectiveness ofvitamin D supplementation in treatment of common diseases. Finally, theprogression in cellular and molecular methods and technology will shed newlights on vitamin D roles in health and disease.

کلیدواژه ها:

Vitamin D ، Antioxidant ، Inflammation ، Gastrointestinal diseases ، Depression