Usefulness of three-phase bone scintigraphy and SPECT/CT for the diagnosis of bone lesions of systemic sarcoidosis

سال انتشار: 1393
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 239

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شناسه ملی سند علمی:

JR_JNMB-2-1_009

تاریخ نمایه سازی: 12 تیر 1398

چکیده مقاله:

We report a three-phase bone scintigraphy for the diagnosis of a peripheral bone lesion caused by systemic sarcoidosis. A 32-year-old man with suspected osteomyelitis of the right forefinger underwent three-phase bone scintigraphy with Tc-99m hydroxymethylene diphosphonate (HMDP) and single-photon emission computed tomography/computed tomography (SPECT/CT). The lesion was rich in blood flow according to flow study and blood pool study on bone scintigraphy, and was associated with an osteolytic change on SPECT/CT imaging performed 3 hours after injection of a radioisotope (RI). Whole-body bone scintigraphy indicated multiple high levels of abnormal RI accumulation. The findings of the three-phase bone scintigraphy and SPECT/CT suggested the presence of systemic sarcoidosis; however, a subsequent 18Ffluorodeoxyglucose positron emission tomography/CT (FDG-PET/CT) could not exclude the possibility of multiple metastases from testicular tumors. Therefore, testicular enucleation was performed, and the pathological examination confirmed the presence of sarcoidosis.

کلیدواژه ها:

Sarcoidosis SPECT/CT Tc-99m HMDP Three-phase bone scintigraphy

نویسندگان

Shigeaki Higashiyama

Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan

Joji Kawabe

Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan

Atsushi Yoshida

Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan

Kohei Kotani

Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan