Fabrication of Biocompatible Surface through Fixation of Silver Nanoparticles Assembled on Polyurethane
محل انتشار: مجله Medbiotech، دوره: 4، شماره: 1
سال انتشار: 1399
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 319
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شناسه ملی سند علمی:
JR_MBT-4-1_007
تاریخ نمایه سازی: 10 خرداد 1399
چکیده مقاله:
Development of simple and reliable protocols for the immobilization of enzymes is an important aspect of nano biotechnology. Silver nanoparticles are known to bind enzymes, but reuse characteristics of the silver nano-enzyme bioconjugates has hithero been poor. In this paper, we demonstrate that silver nanoparticles bound at high surface coverage on polyurethane. This material can be washed, dried, and stored for extended periods without the loss of nanoparticles. The performance of the material is as an antibacterial filter The silver nanoparticle coated on polyurethane then act as templates for the immobilization of the enzyme butyrylcholinesterase (BuChE). BuChE in the bioconjugate system shows enhanced stability toward harsh temperature and pH conditions.
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نویسندگان
Nastaran Astaraki
Iranian-Australian Community of Science, Tehran, Iran
Shima Goudarzi
Iranian-Australian Community of Science, Tehran, Iran