Two novel methods for synthesizing poly (propylenefumarate): Technical aspects and role of vacuum and N2purging effects

سال انتشار: 1395
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 398

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شناسه ملی سند علمی:

JR_POJ-4-1_002

تاریخ نمایه سازی: 29 آذر 1396

چکیده مقاله:

Poly (propylene fumarate) (PPF), a linear unsaturated polyester consisting of alternating propylene glycol and fumaricacid units, can be cured in vivo to fll the skeletal defects with minimal surgical intervention. Many different methodshave been reported for synthesizing PPF, but none of them gives a clear method. The present paper introduces two newmethods in PPF synthesis: Modifed reflux system (MRS) and mixed reflux-distillation system (MRDS). Similarly,the effects of applying vacuum (vacuum sequence, time, vacuum applying position, and the distance between vacuumapplying position and reactor) as well as nitrogen gas (used continuously or only as an N2 blanket) on the PPF synthesishave been studied. The PPF obtained using optimum reaction condition has been characterized by using NMR, FTIR,and GPC analyses. It is demonstrated that the effciency of MRDS in synthesizing PPF is higher than that of MRS.Nitrogen gas, vacuum applying position, continuously/stepwise-continuously applying vacuum and other parametersshow an important role in the polymerization of PPF in both the MRDS and MRS systems. Polyolefns J (2017) 4:27-41

نویسندگان

Sara Shahbazi

Department of Medical Engineering, Amirkabir University of Technology, Tehran, Iran

Yaser Jafari

Department of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran

Fathollah Moztarzadeh

Department of Medical Engineering, Amirkabir University of Technology, Tehran, Iran

Gity Mir Mohammad Sadeghi

Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, P.O. Box: ۱۵۸۷۵-۴۴۱۳, Tehran, Iran