Study of the antibiotic susceptibility profile of the bacterial isolates from the blood samples of the hospitalized patients in Faghihi hospital, Iran 2015-2016
محل انتشار: پنجمین کنگره باکتری شناسی پزشکی ایران
سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 421
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شناسه ملی سند علمی:
MBMED05_076
تاریخ نمایه سازی: 1 دی 1397
چکیده مقاله:
Background: The choice of antimicrobial treatment for septicemia is often empirical and based on the knowledge of local antimicrobial activity patterns of the most common bacteria causing such bloodstream infections. The current study aimed to study the prevalence of bacterial pathogens causing septicemia and their antimicrobial resistance and sensitivity profiles in admitted patients in Shiraz, southwestern Iran. Methods: This cross-sectional study was done at Faghihi hospital, Shiraz, Iran. We examined 1262 positive blood culture from 6300 specimens over a period of one year from September 2015 to September 2016. Results: Bacterial strains were isolated from 20% of blood cultures. Gram-negative bacteria identified were Alcaligenes (29.6%), Escherichia coli (7%), Klebsiella (3.7%), Acinetobacter baumannnii (3.6%), Pseudomonas (2%), Enterobacter (1.2%) and Brucella (1%). In Gram-positive strains Staphylococcus aureus (27.2%), Staphylococcus epidermis (11.4%), non hemolytic streptococci (4.6%), Diphtheroid (4%), Enterococci (3.6%) and Micrococci (0.6%) were the most frequent strains. Imipenem, piperacillin/tazobactam, gentamicin, and amikacin were the antibiotics with most efficacy against Gram-negative agents. Vancomycin, rifampin, cephalothin, and cefazolin were the antibiotics with most efficacies against Gram-negative bacteria agents. Conclusion: Resistance to the majority of the antimicrobial agents for several pathogens implicated in bloodstream infections, particularly in Gram-negative bacteria, can make complications in the treatment of septicemia. We recommend considering better infection control precautions in blood sampling in the hospital
کلیدواژه ها:
نویسندگان
Yalda Malekzadegan
Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences Shiraz, Iran
Mohammad Motamedifar
Shiraz HIV/AIDS Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran
Aida Salehi Nobandegani
Student Research Committee, Shiraz University of Medical Sciences Shiraz, Iran
Elham Rastegar
Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences Shiraz, Iran