Antibiotic susceptibility associated with biofilm production in Acinetobacter baumannii isolated from burn wound colonization

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 415

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شناسه ملی سند علمی:

MBMED05_102

تاریخ نمایه سازی: 1 دی 1397

چکیده مقاله:

Background: Acinetobacter baumannii is consider as an important opportunistic pathogen in hospital whole of the world. Multidrug resistant strains can make very complication in antibiotic therapy and can increase rate of morbidity and mortality in hospitalized patients. Burns patients are in high risk to infect by A. baumannii. This study aims to determine antibiotic susceptibility patterns associated with rate of biofilm production in A. baumannii isolated from burn wound colonization. Methods: In this study 47 isolates of A. baumannii were collected from teaching hospital, Tehran, Iran in 2018. Identifying of bacteria was prepared by conventional biochemical and microbiological methods. Antibiotic susceptibility was done by disc diffusion methods according to CLSI 2018. Tube test was examined for detection the biofilm formation rate in collected strains. Results: All of bacteriawere extensively drug-resistant (XDR) except one isolate. The results of tube test indicated that only 36% of XDR strains are in weak rate of biofilm formation group. Discussion: Presence of XDR strains of A. baumannii is very considerable problem in hospitals. Hence these results are very important for control of nosocomial infection committee in health care systems. On the other hand, this result may indicate that biofilm formation can increase antibiotic resistance next to the other mechanisms of resistance.

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نویسندگان

Mahla Asadian

Division of Microbiology, Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences , Tehran, Iran

Yalda Ostadi

Department of Microbiology, Isfahan University of Medical Sciences, Isfahan, Iran

Sheida Asadpour

Pediatric Infections Research Center, Research Institute for Children Health, Shahid Beheshti University of Medical Sciences, Tehran, Burn Research Center, Iran University of Medical sciences, Tehran, Iran

Faranak Alinejad

Department of Microbiology, Iran University of Medical Sciences, Tehran, Iran