EVALUATION OF ANTIBACTERIAL EFFECTS OF NEUTRAL ELECTROLYZED WATER ON MULTI-DRUG RESISTANT PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM PATIENTS IN GOLESTAN PROVINCE

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 400

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شناسه ملی سند علمی:

MEDISM19_095

تاریخ نمایه سازی: 13 مهر 1397

چکیده مقاله:

Background and Aim:Pseudomonas aeruginosa is an opportunistic bacterium and is one of the main causes of infection in burn patients.This study aims to determine the antibacterial effects of Neutral Electrolyzed Water(NEW) on the growth of multi-drug resistant strains of Pseudomonas aeruginosa.Methods:This descriptive study was carried out on 90 patients that hospitalized in Golestan province Hospitals .Diagnosis tests were used to separate Pseudomonas aeruginosa, and disk diffusion agar method with the Kirby-Bauer standard was applied to determine the pattern of drug-resistance To prepare the Neutral Electrolysis water,sterilized deionized water was mixed with Nacl, hypochlorous acid and sodium hypochlorite and then passed through anode and cathode electrodes after PH=7 confirmation. To determine the NEW antimicrobial properties, sterilized applicators were separately infused with bacterial suspensions , each immersed in a sterile tube filled with NEW at a temperatures of 25 ° C and 37° C.Results:In this study, 34.5% strains were diagnosed as Pseudomonas aeruginosa, out of which 87.09% showed resistance to Ceftazidime, 80.65% to Tobramycin & Cefepime, 77.41% to Gentamicin , 70.98% to Piperacillin and 70.96% to Norfloxacin. Antimicrobial properties of NEW revealed that 86% of resistant isolates and 100% of Sensetive isolates to antibiotics did not grow near NEW. In this study no considerable difference was seen between different temperatures(P<0.05).Conclusion:The results of this study showed that the spread of P.aeruginosa resistant to agents is very high in hospitals, and Neutral Electrolyzed Water proved anti-bacterial effects. Therefore it can be considered for prevention and cure of Burn Wound Infection in the future.

نویسندگان

Shamim Mahmoudianloo

Department of Biology, Gorgan Branch, Islamic Azad University, Gorgan, Iran

Leila Fozouni

Department of Biology, Gorgan Branch, Islamic Azad University, Gorgan, Iran