PREVALENCE OF CITROBACTER FRUNDI BACTERIUM AND ANTIBIOTIC SUSCEPTIBILITY PATTERNS IN ZARREH HOSPITALIZED BURNED PATIENTS SARI, IRAN, 2017

Background and Aim:Citrobacter frundi is an important causative agent of nosocomial infections. Mentioned bacterium owing to the antibiotic resistant patterns has been considered as a main concern in hospitalized patients. The prevalence of C. frundi strains in burned patients and antibiotic susceptibility patterns are the main goals in this survey.Methods:Following the isolation and precise identification of C. frundi species taking advantage of traditional procedure such as oxidase, catalase, motility and others antibiotic susceptibility patters was performed according to the CLSI guide lines by disc diffusion procedure.Results:Out of 3248 Clinical samples 109 (3.35%) C. frundi isolates were identified. Frequency of isolated bacterium from clinical samples were as follows: the wound (72.50%), urine (19.3%), sputum (5.5%), blood (2.8%), and trachea (0%). Susceptibility patterns indicated that, about 10.1% of isolates were susceptible against SXT and 95% of them were resistant to the mentioned antibiotic. Susceptibility and resistance patterns against amikacin virtually were equal (47.7%). Resistant pattern to the cephalexin (93.5%), SXT (87.15), Amikacin (48.62%) were determined to.Conclusion:The findings of this study revealed that amikacin and imipenem are more effective for treatment of the C. frundi in burn patients. So, the fast and accurate evaluation of antibiotic resistance for appropriate antibiotic therapy of patients is imperative.

کلیدواژه ها:

Citrobacter frundi ، burned patiens ، Antibiotic Resistance ، Bacteria