STUDY OF THE ANTIMICROBIAL EFFECTS OF METHANOLIC EXTRACT OF OLIVE LEAVES ON PATHOGENIC STRAINS UNDER LABORATORY CONDITIONS

Background and Aim:Olive leaf is a medicinal plant containing phenolic and oleuripine compounds, which is known as a cheap and affordable source of polyphenols. Phenolic compounds have antioxidant and antimicrobial properties. Today, with the increasing use of antibiotics and also The prevalence of resistant strains, the vacuum resulting from the use of new antimicrobials that have less side effects than antibiotics, is felt. Olive leaf is a medicinal plant that has been used extensively in ancient medicine. In this study, the effect of methanolic extract of this plant on different pathogens is investigated.Methods:In this experimental study, olea europaea was used to evaluate its antimicrobial effects. Methanolic extracts of this plant were prepared at concentrations of 50, 100, 200, 400, 400 mg / ml, and analyzed by Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus and Staphylococcus aureus. The test was to determine the minimum inhibitory concentration and minimum microbial concentration.Results:In this study, the highest effect of methanolic extracts of olive leaves on Pseudomonas aeruginosa Varshakkey was observed at concentrations of 400 mg / ml. The inhibitory concentration of this extract on the growth of these bacteria varied from 6.25 to 100 mg / ml. The minimum germination concentration of the extract from these bacteria was also obtained from 12.5 to 200 mg / ml.Conclusion:In this study, methanolic extracts of ovine leaves were affected by Staphylococcus aureus, Escherichia coli, and Osmosis spp., But did not inhibit Bacillus cereus.

کلیدواژه ها:

Vegetable extract ، olive leaf ، minimum inhibitory concentration