Epidemiology of ocular infection due to Aspergillus species in patients referred to Farabi Hospital

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 365

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شناسه ملی سند علمی:

MEDISM20_181

تاریخ نمایه سازی: 26 بهمن 1398

چکیده مقاله:

Introduction and objectives: Fungal keratitis are the inflammation of cornea due to infection which may result in reduced vision or blindness. In recent years, the incidence of fungal keratitis has increased. The etiologic agents vary as both filamentous fungi and yeasts are implicated as causative agents of fungal keratitis. The aim of this study was to determine the prevalence of Aspergillus infection causing keratomycosis and predisposing factors in Farabi Eye Hospital, Tehran, Iran. Materials and methods: One hundred corneal scrapings from patients with corneal ulcers were taken by ophthalmologist from 2018 to 2019 were analyzed. Corneal scrapings were subjected to KOH wet mount preparation and inoculated on Sabouraud s dextrose agar (SDA) and blood agar medium. Identification to the species level was confirmed by DNA sequencing of the ITS1/ITS2 rDNA region. Results: A total of 27 Aspergillus isolates comprising A. flavus (85.1%) and A. niger (14.9%) were identified. According to our result the male (51.8%) were more affected. The mean age of patients was 47 years (range: 33- 76 years). The corneal trauma with vegetative matter (75%) was the most common predisposing factor. Conclusion: Fungal keratitis due to Aspergillus spp. is a serious ocular illness in young and middle-aged farmers. Farm activity and related ocular trauma were the principal risk factor of fungal keratitis.

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نویسندگان

Alireza Izadi

Department of Medical Mycology and Parasitology, School of Health, Tehran University of Medical sciences, Tehran, Iran

Seyyed Amin Ayatollahi Mousavi

Department of Medical Mycology and Parasitology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran

Mohammad Soleimani

Department of Ocular Trauma and Emergency, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

Sadegh Khodavaisy

Department of Medical Mycology and Parasitology, School of Health, Tehran University of Medical sciences, Tehran, Iran

Seyed Jamal Hashemi

Department of Medical Mycology and Parasitology, School of Health, Tehran University of Medical sciences, Tehran, Iran

Sassan Rezaie

Department of Medical Mycology and Parasitology, School of Health, Tehran University of Medical sciences, Tehran, Iran