A highly efficient synthesis of biologically active spirooxindole derivatives with Nano Fe3O4 as a mild catalyst under solvent-free conditions

سال انتشار: 1394
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 437

فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

MINMETALCONF01_062

تاریخ نمایه سازی: 25 آذر 1395

چکیده مقاله:

In this protocol, we have reported Nano Fe3O4 as an environmentally benign nature catalyst for the multi-component efficient synthesis of biologically spirooxindole derivatives. And we studied three-component efficient synthesis of biologicallyd spirooxindole derivatives. And we studied three-component, one-pot condensation of isatin/acenaphthequinone, malononitrile and different reagents including 1, 3-dicrbonyl compounds, naphthol and 4-hydroxycumarin under thermal and solvent-free conditions in the presence of Nano Fe3O4 as a mild catalyst. solvent-free conditions. short reaction times, good yields, non-toxic, in expensive, simple operational procedures, one-pot, mild, easily separated from the reaction mixture with no column chromatographic separation for the economical synthesis of these fused biologically compounds are the major advantages of this literature.

نویسندگان

Farzaneh Mohamadpour

Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674 Zahedan, Iran

Malek Taher Maghsoodlou

Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674 Zahedan, Iran

Reza Heydari

Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674 Zahedan, Iran