Cancer Stem Cells, their Detection andTreatment

Cancer stem cells have been defined as cells that have the ability to self-renewal, divide andcreate more cancer stem cells. The Change in self-renewal of stem cells, the main stage inthe transformation of normal stem cells into cancer stem cells. Despite is current treatmentshave reduced tumor mass, is not preventing the growth of the tumor that probably relates tocancer stem cells are not destroyed in this treatment. In recent years, cancer stem cells thathave properties which similar to stem cells have reported as the cause of several types ofcancer. Tumorigenic cancer stem cells are separated from non-tumorigenic stem cells withCD24+ and CD44+ cell surface marker. Removal of strategies to inhibit the power of selfrenewalof cancer stem cells, drug delivery pumps, positioning factors can be mentioned. Inthis review, the various types of nanostructures, which have utilized to transfer the specificantibodies on the cancer stem cells, to detection approaches and strategies of eliminating thecancer stem cells are discussed.

کلیدواژه ها:

Cancer Stem Cells ، Self-renewal ، CD24+ ، CD44+ ، Drug delivery pumps ، Positioning factor ، Specific antibodies ، Nanostructures ، Detection ways ، Strategy of Eliminating