Synthesis of new pyrazole derivative with use of Michel intermadiates

سال انتشار: 1393
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 604

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شناسه ملی سند علمی:

NCCHC01_037

تاریخ نمایه سازی: 19 تیر 1394

چکیده مقاله:

In this study, the reaction of malononitrile with three ethylorthoacetat in present of ZnCl2acidic catalyst and aceticacid led to ethoxyethylene malononitrile as Michel intermediats.The reaction above intermediat with hydrazine hydrate in reflax condition new pyrazolederivatives is synthesized. The reaction pyrazole derivatives with threeethylorthoacetat ingrinding condition and in present of hydrazin hydrat, pyrazolo pyrimidine derivatives aresynthesized. In present of benzonitriles and basic catalyst, pyrazolo threazolo pyrimidinederivatives are synthesized.

نویسندگان

Liela Hadipour

Department of Chemistry, Miyaneh Branch, Islamic Azad University, Miyaneh, Iran

Mortaza Mirzaei

Department of Chemistry, Miyaneh Branch, Islamic Azad University, Miyaneh, Iran