Mortality of Congenital Diseases in Mashhad during 2012-2016

Introduction: Congenital diseases and conditions are acquired in utero or at birth. They progress and persistthroughout a person s life. These conditions can be caused from maternal complications, abnormal development,genetic abnormalities, and teratogenic agents. Congenital anomalies are important causes of infant and childhooddeaths, chronic illness and disability. An estimated more than 300 thousand newborns die within 4 weeks of birthevery year, worldwide, due to congenital anomalies. Congenital anomalies can contribute to long-term disability,which may have significant influences on individuals, families, health-care systems, and societies. The mostcommon, severe congenital anomalies are heart defects, neural tube defects and Down syndrome.Methods: In this study data related to 65335 deaths for the period of 2012 to 2016 in Mashhad were analyzed.The sources of the data are: records at the organization for vital records, cemeteries, death certificates, hospitalsand health care senters. The causes of death were coded and classified based on the International Classificationof Diseases-10 edition (ICD-10).Results: The results showed that 65335 deaths were registered, of which 1486 cases (2.27%) were registered dueto congenital malformations, deformations and chromosomal abnormalities, the most common congenitalmalformations of the circulatory system (49.19%). Congenital malformations of the nervous system (13.05%)and other congenital malformations (10.36%) were ranked next. 961 deaths from 1,486 deaths due to congenitalmalformations, deformations and chromosomal abnormalities related to children under one year of age, 623deaths (64.82%) out of 961 deaths were related to the infants (0 to 28 days). The number of deaths due tocongenital malformations, deformations and chromosomal abnormalities is higher for men (53.43%) than forwomen (46.57%).Conclusion: In conclusion although, many anomalies are not preventable, it is suggested to focus more ongenetic studies in the field of cardiovascular disease and the nervous system.

کلیدواژه ها:

Mortality ، Congenital Diseases ، Mashhad