Synbiotic supplementation and obesity in children: A systematic review

Introduction: Over the course of time there has been a considerable increase in the prevalence of obesity in children. The factors associated with obesity are complex, and include life style, such as eating habits and physical activity, environmental and biological determinants influence in life style. The intestinal microbiota has several functions related to host health and some evidence indicates that the gut microbiota is connected with the increase of obesity, obesity-associated inflammation and insulin resistance. Synbiotic supplementation have been shown to decrease food intake and reduce body fat in overweight and obese adults; such experience is limited in children and adolescents. This systematic review will evaluate the recent scientific literature on the efficacy of the probiotics supplementation on promoting weight loss in obese children. Methods: We performed a systematic search by using relevant keywords on online medical databases including: PubMed/Medline, Scopus and Google scholar.Results: reviewed in this article indicate that Independent of other lifestyle factors, prebiotic and probiotic supplementation in children with overweight and obese helps to: regulate in appetite, reduce oxidative stress, and Changes in body mass index, and triceps skinfold thickness which significantly reduce body weight in children with obesity.Conclusion: In summary Prebiotic and probiotic supplementation can be a helpful tool to treat obesity in children.

کلیدواژه ها:

probiotic ، synbiotic ، obesity ، children ، systematic review