The effectiveness of mindfulness-based stress reduction therapy on cortisol level and quality of life in a patient with posttransplant lymphoproliferative disorders, a single-case experimental study

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 372

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شناسه ملی سند علمی:

NSCMED08_415

تاریخ نمایه سازی: 15 دی 1398

چکیده مقاله:

Background and Aim : Lymphoproliferative disease is a known disorder of organ transplantation, which its delayed diagnosis and delayed treatment leads to the death of patients. Increasing the quality of life and survival time of patients undergoing liver transplantation are among the concerns of the medical staff. The aim of this study was to investigate the effectiveness of mindfulness-based stress reduction therapy on quality of life.Methods : In a single case experimental study, during June to December 2016, a 7-year-old boy with anxiety syndrome who had undergone liver transplantation one year before the present study was selected purposefully and in the form of ABCABC reversal design with multiple baselines was treated with mindfulness-based stress reduction for six weeks. Evaluation of two indices of cortisol and quality of life was carried out twice a week. Cortisol levels were collected through salvia test and analyzed using an enzyme-linked immunosorbent assay (ELISA). Data were analyzed by generalized estimation equation and repeated measures correlation.Results : The primary outcomes showed that treatment of mindfulness was associated with a decrease in the level of salivary cortisol (p<0.01). Significant improvements were also observed in the quality of life index, although this index has a borderline significance (p= 0.048). In addition, secondary outcomes suggest an inverse relationship between the two indicators of cortisol and quality of life.Conclusion : The results of this study, in line with the research background, indicate the effective role of psychological interventions in management of diseases caused by immune system weakness. Further studies in the form of controlled clinical trials can be a good route for future studies.

کلیدواژه ها:

Posttransplant Lymphoproliferative Disorders ، Mindfulness-based stress reduction therapy ، Cortisol ، Quality of life

نویسندگان

Bijan Pirnia

PhD Student of Clinical Psychology, Department of Psychology, Faculty of Humanities, University of Science and Culture, Tehran, Iran. Behavioral Sciences Research Center of Shahid Beheshti University of Medical Sciences, Tehran, Iran

Nagar Sadegh Esfahani

M.A in Clinical Psychology, Department of Psychology, Islamic Azad University of Karaj Branch, Karaj, Iran

Kambiz Pirnia

M.D, Internal disease specialist, Technical Assistant in Bijan Center for Substance Abuse Treatment, Tehran, Iran

Shania Haghighat

PhD Student of Psychology, Department of Psychology, Islamic Azad University of Science and Research, Tehran, Iran

Paria Sadeghi

M.A in Psychology of Personality, Islamic Azad University of Science and Research, Tehran, Iran