The Impact of Obesity on Male Fertility

Background: Infertility is defined as a couple’s inability to achieve pregnancy following one year of unprotected inter-course. Male factors alone constitute 25-30% of all cases of infertility. It seems that obesity is associated with reduced male fertility. The rate of obesity among young men is constantly increasing and the rate of obesity has more than doubled over the past decade and it is a major health problem throughout the world. This review focuses on negative impact of obesity in men fertility and the benefits of weight loss on reproductive outcomes.Materials and Methods: This review article has been extract-ed from 28 articles that has indexed in most valid scientific cites that has published from year 2012 to 2019.Results: Some etiology for male infertility include cryptor-chidism, testicular torsion or trauma, varicocele, seminal tract infections, antisperm antibodies, gonadal dysgenesis, and ob-struction of the reproductive channels. Obesity was recently proposed for addition to this list. the relationship between obe-sity and semen characteristics, reproductive endocrine function, sexual function, and male infertility is found. Obesity increase estrogen and it is an inverse correlation between obesity and testosterone and a direct correlation with estrogen. Obesity is probably due to the interaction between multiple genes and several environmental factors, including diet and activity level. Obesity is often associated with a lifestyle characterized by decreased physical activity with prolonged periods of sitting, which has been shown to affect sperm production by increasing local testicular temperatureObese infertile men can also have a characteristic scrotal fat deposition that can increase the lo-cal testicular temperature and affect sperm production. Another potential cause for infertility in obese men is the reduced coital frequency associated with obesity. In men reporting symptoms of erectile dysfunction, overweight or obesity are found in 79% of subjects.Conclusion: In obese males, evidence suggests that increased estrogen as a result of aromatization in the fatty tissue may be an important mechanism for the hypoandrogenemia and altered sperm parameters. There is evidence that weight reduction can correct this hormonal imbalance. Weight loss is the cornerstone of the treatment of obesity-associated infertility. Most studies have focused on the effects of weight loss on the hormonal pro-file of obese men. In addition, physical activity and leanness are associated with a reduced risk for erectile dysfunction. Lifestyle changes that encourage weight loss, including diet and exercise Then can improve in erectile dysfunction.

کلیدواژه ها:

Infertility ، Obesity ، Men ، Exercise