Evaluation of total phenolic, flavonoid compounds and antioxidant activity of aqueous extract of Artemisia annua

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 353

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شناسه ملی سند علمی:

TOXICOLOGY15_166

تاریخ نمایه سازی: 15 بهمن 1398

چکیده مقاله:

Background and purpose: Artemisia annua belongs to the plant family of Asteraceae and is an annual short-day plant.Artemisia annua distribution Widespread in forested areas of northern Iran. In this study, antioxidant properties, total Phenolic, flavonoid compounds of aqueous extract were investigated.Materials and methods: Extraction was done by maceration method. Total amount of phenolic and flavonoid compounds of the extract was determined by spectrophotometric method. Anti-Radical Activity of Extract by DPPH Free Radical Coupling Test and Frequency Antioxidant-Reducing Activity (FRAP) Evaluation.The collected data were analyzed using Excel software.Results: The extract had higher total phenolic content than total flavonoid content. The aqueous extract showed moderate DPPH radical effect.Conclusion: The results of this study showed that Artemisia annua as a rich and potential source of biocomponents.It is an active antioxidant used in the food and drug industry to maintain human health.

نویسندگان

Mahshid Ghanbari

Master student of toxicoloy , Department of Pharmacology and Toxicology, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran

Mohammad Shokrzadeh

Assistant Professor, Department of Pharmacology and Toxicology, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran

Forouzan Sadeghimahalli

Assistant Professor, Department of Pharmacology and Physiology, School of Medical, Mazandaran University of Medical Sciences, Sari, Iran

Emran Habibi

Assistant Professor, Department of Pharmacognosy, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran