A STUDY OF TENSILE CYCLIC LOADING ON THE MORPHOLOGY OF CULTURED ENDOTHELIAL CELLS WITH APPLICATIONS OF FRACTAL ANALYSIS
عنوان مقاله: A STUDY OF TENSILE CYCLIC LOADING ON THE MORPHOLOGY OF CULTURED ENDOTHELIAL CELLS WITH APPLICATIONS OF FRACTAL ANALYSIS
شناسه ملی مقاله: ISME15_424
منتشر شده در پانزدهمین کنفرانس سالانه مهندسی مکانیک در سال 1386
شناسه ملی مقاله: ISME15_424
منتشر شده در پانزدهمین کنفرانس سالانه مهندسی مکانیک در سال 1386
مشخصات نویسندگان مقاله:
Amini - Msc. student, Amirkabir University of Technology, Tehran, Iran
Tafazzoli Shadpour - Assistant professor, Amirkabir University of Technology, Tehran, Iran
Haghighipour - PhD student, Amirkabir University of Technology, Tehran, Iran
خلاصه مقاله:
Amini - Msc. student, Amirkabir University of Technology, Tehran, Iran
Tafazzoli Shadpour - Assistant professor, Amirkabir University of Technology, Tehran, Iran
Haghighipour - PhD student, Amirkabir University of Technology, Tehran, Iran
Morphological remodeling of endothelial cells induced by blood flow and pressure is considered as an adaptive response to mechanical stimuli. To determine the mechanism of response, we examined the change in the morphology of endothelial cells caused by cyclic strain. Here, we have described a new, digital image analysis method that has been adapted to evaluate fractal dimension of cellular profiles as a measure of morphological complexity. The fractal dimension seemed to be a suitable parameter for the analysis of morphological changes of endothelial cells caused by mechanical parameters such as cyclic stretch due to blood pressure.
کلمات کلیدی: endothelial cells, cyclic strain, fractal dimension, cell morphology, image analysis
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/29040/