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گواهی نمایه سازی مقاله Monitoring the Effect of Flow rate on Size and Morphology of Microspheres Produced by the Means of Electrospraying Method

عنوان مقاله: Monitoring the Effect of Flow rate on Size and Morphology of Microspheres Produced by the Means of Electrospraying Method
شناسه (COI) مقاله: ISPST10_733
منتشر شده در دهمین سمینار بین المللی علوم و تکنولوژی پلیمر در سال ۱۳۹۱
مشخصات نویسندگان مقاله:

Milad Jafari-Nodoushan - Science Department, Iran Polymer and Petrochemical Institute, Tehran, Iran.
Hamid Mobedi - Science Department, Iran Polymer and Petrochemical Institute, Tehran, Iran.
Jalal Barzin - Science Department, Iran Polymer and Petrochemical Institute, Tehran, Iran.

خلاصه مقاله:
There are numerous drug-delivery systems and the goal of most of these is to deliver medications intact to specific targets in the body through a medium that can control theadministration of therapy by means of either a physiological or chemical trigger. One of the most important characteristics to achieve this goal is particle size, which has a significant effect upon the in vivo behaviour such as circulation time, extravasation, targeting, immunogenicity, internalization,intracellular trafficking, degradation, flow properties, clearance and uptake mechanisms [1]. Electrohydrodynamic atomization (EHDA) is frequently usedin analytical chemistry for the production of highly charged, gas phase ions because size controllable near-monodisperse droplets are produced in electrohydrodynamic atomization, it has the potential for use in the production of controlled size polymer particles [2].

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