Elahe abdollahi - Department of Chemistry, Amirkabir University of Technology, Tehran, Iran,Faculty of Pharmacy, Department of Drug and Food Control, Tehran University of Medical Sciences, Enghelab St., Tehran 14155-6451, Iran.
majid abdouss - Department of Chemistry, Amirkabir University of Technology, Tehran, Iran,
ali mohammadi - Faculty of Pharmacy, Department of Drug and Food Control, Tehran University of Medical Sciences, Enghelab St., Tehran 14155-6451, Iran.
saeed yaripour - Faculty of Pharmacy, Department of Drug and Food Control, Tehran University of Medical Sciences, Enghelab St., Tehran 14155-6451, Iran.

This paper describes novel synthetic conditions of precipitation polymerization to obtain uniformly sized molecularly imprinted nano-spheres of hydantoins for application in design of the new drug delivery systems. In addition, the structure, morphology, thermal stability, thermal behavior and binding properties of molecularly imprinted polymers (MIPs) were studied. The imprinted nanospheres showed excellent binding properties and had 10-15% higher template binding compared to its blank polymer. Polymers with high thermal stability were obtained and unleached polymer particles showed higher thermal stability than leached MIP particles

Molecular imprinting, polymer, drug delivery, nano particle, molecular binding