Somayeh Heydari - Department of Chemistry, University of Torbat-e jam, Torbat-e jam, Iran

Green synthesis of metal nanoparticles is an interesting issue of nanoscience due to its simplicity and eco-friendliness. The present study describes a cheaper, non-toxic and simple route for biosynthesis of nickel nanoparticles using Phlomis cancellata Bunge extracts. Since the experimental conditions of this procedure play vital roles in the synthesis rate of the nanoparticles, a response surface methodology using the central composite design was employed for testing the reaction variables. The individual and interactive effects of process variables (temperature, time, concentration of Ni(NO3)2 and pH) upon extracellular biological synthesis of NiNPs by Phlomis cancellata Bunge were studied. The statistical and perturbation plot analysis suggest that a reaction temperature of 09 °C, duration of 39 min., pH of 0.9 and concentration of 22 mM of Ni(NO3)2 would produce the highest amount of nanoparticles. The nanoparticles were characterized by UV-Visible spectrophotometry

response surface methodology, green synthesis, nickel nanoparticles, Phlomis cancellata Bunge