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CRISPR in neuroscience and neurology

عنوان مقاله: CRISPR in neuroscience and neurology
شناسه ملی مقاله: NGCMED10_134
منتشر شده در دومین کنگره بین ‎‎المللی و دهمین همایش ملی نوروژنتیک ایران در سال 1396
مشخصات نویسندگان مقاله:

Omid Aryani - Department of Neuroscience (IUMS), Tehran-Iran- Endocrinology and Metabolic Research Institute (TUMS), Tehran-IranBrain and Cognition Clinic (IUMS/IRICSS), Tehran-Iran
Mohammad Tahi Joghataei

خلاصه مقاله:
Since it was first used to edit the mammalian genome, the targetable gene editing tool CRISPR (clusteredregularly interspaced short palindromic repeats) has become widely accessible to researchers. CRISPR’spotential in neuroscience ranges from investigating fundamental processes underlying brain function anddevelopment, to modelling neurological diseases in both animals and cells, and perhaps to CRISPR-basedtherapies. I will discuss on CRISPR’s current applications in cell and animal models aiming to clarify brainfunction and dysfunction, and some of the challenges that currently limit CRISPR’s use in neuroscience and ourexperiences in Iran

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/744982/