Yahya Attaran - M.D, FCAP, Assistant professor of Pathology, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran
Simin Moghdam - M.D, Department of Pathology, Beheshti Hospital, Shiraz, Iran
Ahmad Monabati - M.D, Professor of Pathology, Department of Pathology and Hematology Research Center, Shiraz University of Medical sciences, Shiraz, Iran
Reza Sarkeshikian - M.D, Pasteur Pathobiology Laboratory, Shiraz, Iran

Lymphoepithelial - like carcinoma, is rarely recognized in the urinary bladder and less commonly occurs with papillary transitional cell carcinoma i.e. mixed pattern. Also, less uncommon is the occurrence of carcinoma in situ changes in the adjacent urothelium of these tumors. Here, a case of lymphoepithelial – like carcinoma and papillary transitional cell carcinoma associated with carcinoma in situ changes of urothelium of the urinary bladder has been reported the prognosis of this type of malignancy as well as its management will be discussed. Meanwhile, immunohistochemical stains have been carried out to differentiate it from lymphoma of the urinary bladder and the findings will be discussed.

Urinary bladder, like carcinoma, Carcinoma in situ